Breakthrough method for determination of empty versus full AAV capsids

The need to determine the ratio of full, partial and empty capsids is a critical part of the development process.

Today’s methods, however, are complex and expensive, use a significant amount of samples, and return resuts that are difficult to analyze. Until now.

Discover an easily optimized method that:

  • Utilizes a minute amount of sample and employs high resolving power to determine the ratio of full and empty capsids
  • Obtains the ratio of capsids in less than 1 hour per sample
  • Separates capsids, product and product-related impurities by isoelectric point (pI)

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